Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid Dimethyl Ester SCHEMBL419177 | 0.89 | DGKA (0.50) | DGKACA12CA2CA7CA9 | |
| Sulfuric Acid Dimethyl Ester SCHEMBL422526 | 0.87 | DGKA (0.48) | DGKACA12CA2CA7CA9 | |
| SCHEMBL5290259 | 0.86 | DGKA (0.64) | DGKALMNANAAAPAMMAPT | |
| SCHEMBL28012 | 0.86 | DGKA (0.64) | DGKALMNANAAAPAMMAPT | |
| SCHEMBL80831 | 0.86 | DGKA (0.64) | DGKALMNANAAAPAMMAPT | |
| SCHEMBL8859535 | 0.86 | DGKA (0.64) | DGKALMNANAAAPAMMAPT | |
| SCHEMBL2296513 | 0.86 | DGKA (0.64) | DGKALMNANAAAPAMMAPT | |
| SCHEMBL18585982 | 0.86 | DGKA (0.64) | DGKALMNANAAAPAMMAPT | |
| SCHEMBL247955 | 0.86 | DGKA (0.64) | DGKALMNANAAAPAMMAPT | |
| SCHEMBL247933 | 0.86 | DGKA (0.64) | DGKALMNANAAAPAMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109090809-A | For applying the application device component of composition | 宝洁公司 | 2018-12-28 | — | — | CN | disclosed |