Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | PTGIR | P43119 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23402918 | 0.83 | CNR1 (0.49) | CNR1CNR2SMPD1PTGIRMEN1 | |
| SCHEMBL28272012 | 0.78 | POLB (0.49) | MEN1KMT2A | |
| SCHEMBL24221989 | 0.76 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL8874913 | 0.75 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL23399610 | 0.74 | NR1H3 (0.54) | CNR1CNR2PTGIRMEN1CYP1A2 | |
| SCHEMBL11873211 | 0.74 | MEN1 (0.58) | PTGIRMEN1CYP1A2CYP2C9CRHBP | |
| SCHEMBL8888843 | 0.73 | MEN1 (0.53) | CNR1CNR2SMPD1PTGIRMEN1 | |
| SCHEMBL23402096 | 0.72 | NR1H3 (0.49) | CNR1CNR2PTGIRMEN1CYP1A2 | |
| SCHEMBL23399801 | 0.72 | NR1H3 (0.49) | CNR1CNR2PTGIRMEN1CYP1A2 | |
| SCHEMBL23398901 | 0.71 | NR1H3 (0.48) | CNR1CNR2PTGIRMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232426-A | A kind of N- hydroxyl -5- substitution -1H- pyrazole-3-formamide compound and its preparation method and application | 中国药科大学 | 2019-01-18 | — | — | CN | disclosed |