Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.42 |
| ▸ | CDK2 | P24941 | 5/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL280162 | 0.85 | CSF1R (0.46) | POLBCA1CA2GRM5KDM4E | |
| SCHEMBL30900619 | 0.80 | GRM5 (0.58) | POLBCA1CA2GRM5KDM4E | |
| SCHEMBL28271968 | 0.78 | CNR1 (0.54) | KMT2AMEN1 | |
| SCHEMBL11674731 | 0.75 | MEN1 (0.50) | POLBCA1CA2KDM4ELMNA | |
| SCHEMBL14154662 | 0.75 | ALDH1A1 (0.52) | POLBCA1CA2KDM4EADORA2A | |
| SCHEMBL21408239 | 0.74 | POLB (0.56) | POLBCA1CA2KDM4ELMNA | |
| SCHEMBL7755885 | 0.74 | MAPT (0.49) | POLBCA1CA2GRM5KDM4E | |
| SCHEMBL30988460 | 0.73 | GRM5 (0.59) | CA1CA2GRM5 | |
| SCHEMBL27850030 | 0.72 | MAP2K1 (0.48) | POLBKDM4ECLK4DYRK1BKMT2A | |
| SCHEMBL1483542 | 0.72 | KDM5A (0.46) | LMNAKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232426-A | A kind of N- hydroxyl -5- substitution -1H- pyrazole-3-formamide compound and its preparation method and application | 中国药科大学 | 2019-01-18 | — | — | CN | disclosed |