Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30736468 | 1.00 | TERT (0.67) | TERTNR1H4KDM4EMEN1ALDH1A1 | |
| SCHEMBL31436362 | 1.00 | TERT (0.67) | TERTNR1H4KDM4EMEN1ALDH1A1 | |
| SCHEMBL28488132 | 1.00 | TERT (0.67) | TERTNR1H4KDM4EMEN1ALDH1A1 | |
| SCHEMBL2541144 | 0.85 | TERT (0.70) | TERTNR1H4KDM4EMEN1ALDH1A1 | |
| SCHEMBL30736439 | 0.85 | TERT (0.70) | TERTNR1H4KDM4EMEN1ALDH1A1 | |
| SCHEMBL2541146 | 0.85 | TERT (0.70) | TERTNR1H4KDM4EMEN1ALDH1A1 | |
| SCHEMBL31436349 | 0.85 | TERT (0.70) | TERTNR1H4KDM4EMEN1ALDH1A1 | |
| SCHEMBL30736445 | 0.83 | CYP1B1 (0.68) | TERTNR1H4ALDH1A1MAOAMAOB | |
| SCHEMBL31436356 | 0.83 | CYP1B1 (0.68) | TERTNR1H4ALDH1A1MAOAMAOB | |
| SCHEMBL25265116 | 0.82 | MAOB (0.73) | KDM4EMEN1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265332-B | Polyhydroxy chalcone compound and application thereof | 北京理工大学 | 2020-11-13 | — | — | CN | claimed |
| CN-109265332-A | A kind of polyhydroxy chalcone compound and application thereof | 北京理工大学 | 2019-01-25 | — | — | CN | claimed |
| CN-109265332-B | Polyhydroxy chalcone compound and application thereof | 北京理工大学 | 2020-11-13 | — | — | CN | disclosed |
| CN-109265332-A | A kind of polyhydroxy chalcone compound and application thereof | 北京理工大学 | 2019-01-25 | — | — | CN | disclosed |