SCHEMBL2827346

SCHEMBL2827346

CCCCCCCCc1ccc(Nc2ccc3ccccc3c2CCCCCCCC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.42
UNG P13051 3/20 0.41
NCEH1 Q6PIU2 1/20 0.41
ESR1 P03372 2/20 0.40
ADRA2A P08913 2/20 0.40
ADORA3 P0DMS8 2/20 0.40
TACR2 P21452 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
SLC6A3 Q01959 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
SHBG P04278 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
HSPD1 P10809 1/20 0.40
ADRB3 P13945 1/20 0.40
HTR2C P28335 1/20 0.40
HSPE1 P61604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11692052 0.91 ALDH1A1 (0.46) NCEH1KDM4EALDH1A1LMNATP53
SCHEMBL11693293 0.91 ALDH1A1 (0.46) NCEH1KDM4EALDH1A1LMNATP53
SCHEMBL8391802 0.91 ALDH1A1 (0.46) NCEH1KDM4EALDH1A1LMNATP53
SCHEMBL294932 0.85 ALDH1A1 (0.54) HTR2AUNGESR1ADRA2AADORA3
SCHEMBL1705432 0.85 ALDH1A1 (0.54) HTR2AUNGESR1ADRA2AADORA3
SCHEMBL29382146 0.85 ALDH1A1 (0.54) HTR2AUNGESR1ADRA2AADORA3
SCHEMBL293780 0.85 ALDH1A1 (0.54) HTR2AUNGESR1ADRA2AADORA3
SCHEMBL110264 0.85 ALDH1A1 (0.54) HTR2AUNGESR1ADRA2AADORA3
SCHEMBL27919204 0.80 NCEH1 (0.46) NCEH1KDM4EALDH1A1LMNAHSD17B10
SCHEMBL27937768 0.80 NCEH1 (0.46) NCEH1KDM4EALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1121404-B1 HIGH PERFORMANCE LUBRICATING OILS EXXONMOBIL OIL CORP (US) 2016-02-03 EP disclosed
EP-2021440-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2015-07-01 EP disclosed
US-8476205-B2 Chromium HVI-PAO bi-modal lubricant compositions EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-07-02 US disclosed
US-8399390-B2 HVI-PAO in industrial lubricant and grease compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-03-19 US disclosed
US-8273694-B2 Synthetic compositions obtained from algae Brown, Jeffrey A (US) 2012-09-25 US disclosed
EP-2344581-B1 IMPROVED HVI-PAO BI-MODAL LUBRICANT COMPOSITIONS EXXONMOBIL RES & ENG CO (US) 2012-06-27 EP disclosed
EP-2194114-A2 Lubricating composition Shell Internationale Research Maatschappij B.V. (NL) 2010-06-09 EP disclosed
US-20100120643-A1 Synthetic compositions obtained from algae YUTOMI, INC. 2010-05-13 US disclosed
US-20100105589-A1 Chromium HVI-PAO bi-modal lubricant compositions EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2010-04-29 US disclosed
EP-2159275-A2 Lubricating composition Shell Internationale Research Maatschappij B.V. (NL) 2010-03-03 EP disclosed
US-5562864-A OIL WITH ONE CARBOXY DERIVATIVE FORMED BY ACYLATION OF SUCCINIC ACID AND A MIXTURE OF OVERBASED SALT OF CARBOXYLIC ACID, OR ACID WITH SULFONIC ACID WITH MAGNESIUM OR CALCIUM COMPOUNDS THE LUBRIZOL CORPORATION (US) 1996-10-08 US disclosed
EP-0712834-A1 High oleic polyol esters, compositions and lubricants functional fluids and greases containing the same THE LUBRIZOL CORPORATION (US) 1996-05-22 EP disclosed
US-5490945-A OIL CONTAINING CARBOXYLIC MODIFIED POLYOLEFIN THE LUBRIZOL CORPORATION (US) 1996-02-13 US disclosed
EP-0535221-B1 LUBRICATING COMPOSITIONS LUBRIZOL CORP (US) 1996-01-31 EP disclosed
US-5486300-A Lubricating compositions THE LUBRIZOL CORPORATION (US) 1996-01-23 US disclosed
EP-0678569-A2 Lubricating compositions with improved oxidation resistance containing a dispersant and an antioxidant THE LUBRIZOL CORPORATION (US) 1995-10-25 EP disclosed
EP-0471071-B1 HIGH TEMPERATURE FUNCTIONAL FLUIDS LUBRIZOL CORP (US) 1995-08-30 EP disclosed
EP-0596048-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1994-05-11 EP disclosed
WO-1993023504-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1993-11-25 WO disclosed
WO-1991013133-A2 HIGH TEMPERATURE FUNCTIONAL FLUIDS THE LUBRIZOL CORPORATION (US) 1991-09-05 WO disclosed