SCHEMBL28273634

SCHEMBL28273634

Cc1cc(-c2ccccc2)c(C)c(C)c1C.[NaH]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.45
CYP2A6 P11509 1/20 0.43
CYP2B6 P20813 1/20 0.43
SQOR Q9Y6N5 1/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
BACE1 P56817 1/20 0.41
PTGS1 P23219 1/20 0.41
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
PSMB5 P28074 2/20 0.37
AKT1 P31749 1/20 0.36
AKT2 P31751 1/20 0.36
ADORA3 P0DMS8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128036 0.98 ESR2 (0.47) ESR2CYP2A6CYP2B6SQORALDH1A1
SCHEMBL30954899 0.95 ESR2 (0.45) ESR2CYP2A6CYP2B6SQORALDH1A1
Water SCHEMBL3331289 0.95 ESR2 (0.45) ESR2CYP2A6CYP2B6SQORALDH1A1
SCHEMBL28533212 0.95 ESR2 (0.45) ESR2CYP2A6CYP2B6SQORALDH1A1
SCHEMBL28805622 0.95 ESR2 (0.45) ESR2CYP2A6CYP2B6SQORALDH1A1
Biphenyl SCHEMBL18106197 0.95 ESR2 (0.45) ESR2CYP2A6CYP2B6SQORALDH1A1
Water SCHEMBL1538411 0.95 ESR2 (0.45) ESR2CYP2A6CYP2B6SQORALDH1A1
Ammonia Solution, Strong SCHEMBL15862223 0.95 ESR2 (0.45) ESR2CYP2A6CYP2B6SQORALDH1A1
Biphenyl SCHEMBL27656465 0.95 ESR2 (0.45) ESR2CYP2A6CYP2B6SQORALDH1A1
Hydrogen Peroxide SCHEMBL28104708 0.95 ESR2 (0.50) ESR2CYP2A6CYP2B6SQORALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109206552-A A kind of hybrid cross-linked dynamic aggregation object 翁秋梅 2019-01-15 CN disclosed