Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL5985807 | 0.88 | — | — | |
| Monoethanolamine SCHEMBL21465320 | 0.83 | TSHR (0.50) | — | |
| Monoethanolamine SCHEMBL1834156 | 0.80 | TSHR (0.67) | — | |
| Monoethanolamine SCHEMBL1263481 | 0.80 | — | — | |
| Urea SCHEMBL2597672 | 0.80 | — | — | |
| Ethylene Glycol SCHEMBL5133455 | 0.79 | — | — | |
| Ethylene Glycol SCHEMBL27514008 | 0.79 | TSHR (0.50) | — | |
| Monoethanolamine SCHEMBL1332111 | 0.78 | — | — | |
| Monoethanolamine SCHEMBL1331364 | 0.78 | — | — | |
| Monoethanolamine SCHEMBL14675689 | 0.78 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105349593-B | A kind of preparation method of pethidine hydrochloride | 浙江汇能生物股份有限公司 | 2019-01-25 | — | — | CN | disclosed |