Cetalkonium

Cetalkonium

SCHEMBL28274356

CCCCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1.O=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.60
KMT2A Q03164 3/20 0.59
MEN1 O00255 2/20 0.59
MAPK1 P28482 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
TP53 P04637 1/20 0.59
HTT P42858 4/20 0.58
LMNA P02545 2/20 0.51
CA12 O43570 2/20 0.51
CA9 Q16790 2/20 0.51
KDM4E B2RXH2 1/20 0.51
USP2 O75604 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
BCHE P06276 1/20 0.51
CA4 P22748 1/20 0.51
CA6 P23280 1/20 0.51
CA5A P35218 1/20 0.51
CA7 P43166 1/20 0.51
CA14 Q9ULX7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Miristalkonium Ion SCHEMBL27923387 1.00 DNM1 (0.60) DNM1KMT2AMEN1MAPK1SMN1; SMN2
Didecyldimethylammonium SCHEMBL28160713 0.90 KMT2A (0.59) DNM1KMT2AMEN1MAPK1SMN1; SMN2
Cetrimonium SCHEMBL196676 0.85 CA12 (0.59) DNM1KMT2ALMNACA12CA9
Saccharin SCHEMBL196947 0.85 CA12 (0.59) DNM1KMT2ALMNACA12CA9
Cetrimonium SCHEMBL28582109 0.84 CA12 (0.58) DNM1KMT2ALMNACA12CA9
Cetrimonium SCHEMBL28101522 0.84 CA12 (0.58) DNM1KMT2ALMNACA12CA9
Tetrabuthylammonium SCHEMBL27547504 0.81 CA12 (0.65) KMT2AHTTLMNACA12CA9
Tetradecane SCHEMBL10356237 0.80 CA12 (0.55) KMT2AHTTLMNACA12CA9
Dodecane SCHEMBL10356317 0.80 CA12 (0.55) KMT2AHTTLMNACA12CA9
Benzododecinium SCHEMBL28637937 0.78 DNM1 (0.87) DNM1KMT2AMEN1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110300595-A PAC1 receptor stimulating agent (MAXCAP) and application thereof 加利福尼亚大学董事会 2019-10-01 CN disclosed
CN-104995176-B Hydantoins that modulate BACE mediated APP processing 巴克老龄化研究所 2019-02-22 CN disclosed