SCHEMBL28275409

SCHEMBL28275409

CCCCCC(CC)n1ccnn1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.34
OPRM1 P35372 1/20 0.33
TLR8 Q9NR97 2/20 0.32
TBXAS1 P24557 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23771912 0.91 CYP19A1 (0.35) CYP19A1OPRM1TBXAS1
SCHEMBL20031996 0.91 CYP19A1 (0.35) CYP19A1OPRM1TLR8TBXAS1
SCHEMBL20729403 0.91 CYP19A1 (0.35) CYP19A1OPRM1TBXAS1
SCHEMBL19226278 0.91 CYP19A1 (0.35) CYP19A1OPRM1TBXAS1
SCHEMBL19302676 0.91 CYP19A1 (0.35) CYP19A1OPRM1TBXAS1
SCHEMBL13550397 0.87 CYP19A1 (0.36) CYP19A1
SCHEMBL12369613 0.82 CYP19A1 (0.41) CYP19A1
Bromide SCHEMBL29191437 0.81 OPRM1 (0.36) CYP19A1OPRM1TBXAS1
SCHEMBL11194903 0.80 OPRM1 (0.39) CYP19A1OPRM1TLR8TBXAS1
SCHEMBL20397465 0.79 CYP19A1 (0.34) CYP19A1OPRM1TLR8TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311898-A [8- (phenylsulfonyl) -3, 8-diazabicyclo [3.2.1] oct-3-yl ] (1H-1,2, 3-triazol-4-yl) methanone 拜耳医药股份有限公司 2019-02-05 CN claimed