⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924939 | 0.80 | — | — | |
| SCHEMBL27468423 | 0.80 | CPN1 (0.44) | — | |
| SCHEMBL27517189 | 0.77 | CPN1 (0.37) | — | |
| SCHEMBL919243 | 0.77 | — | — | |
| SCHEMBL25538094 | 0.75 | GBA1 (0.32) | — | |
| SCHEMBL919367 | 0.73 | SHBG (0.42) | — | |
| SCHEMBL921142 | 0.73 | — | — | |
| SCHEMBL841662 | 0.71 | SHBG (0.46) | — | |
| SCHEMBL11831532 | 0.71 | SHBG (0.46) | — | |
| SCHEMBL11629006 | 0.71 | SHBG (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311889-A | Activin receptor-like kinase inhibitors | 蓝图药品公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109311889-A | Activin receptor-like kinase inhibitors | 蓝图药品公司 | 2019-02-05 | — | — | CN | disclosed |