Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | PDE9A | O76083 | 4/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | GUSB | P08236 | 1/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | CLPP | Q16740 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329347 | 0.80 | RAB9A (0.77) | TYMSKDM4ERAB9AAPPTP53 | |
| SCHEMBL11637387 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1RAB9AMAOBTNKS | |
| SCHEMBL32666100 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1RAB9AMAOBTNKS | |
| SCHEMBL18934419 | 0.74 | KDM4E (0.74) | KDM4EALDH1A1RAB9ATNKSTNKS2 | |
| SCHEMBL22119586 | 0.74 | PDE9A (0.56) | TYMSPDE9ACLPPTP53 | |
| SCHEMBL18934416 | 0.72 | KDM4E (0.70) | KDM4EALDH1A1RAB9ATNKS2SMN1; SMN2 | |
| SCHEMBL30289873 | 0.72 | KDM4E (0.71) | KDM4EALDH1A1RAB9ATNKSGUSB | |
| SCHEMBL16981654 | 0.72 | PDE9A (1.00) | PDE9A | |
| SCHEMBL3106597 | 0.71 | APP (0.85) | KDM4EALDH1A1APPPDE5A | |
| SCHEMBL16280938 | 0.71 | RAD52 (0.79) | KDM4EALDH1A1APPPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422697-A | The method for synthesizing Quinazol derivative | 南京理工大学 | 2019-03-05 | — | — | CN | disclosed |