Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2025544 | 1.00 | CHKA (0.37) | CHKAHTTKMT2AHRH3FASN | |
| SCHEMBL2302192 | 0.86 | CHKA (0.41) | CHKAHTTKMT2AHRH3FASN | |
| SCHEMBL2021298 | 0.86 | CHKA (0.41) | CHKAHTTKMT2AHRH3FASN | |
| SCHEMBL2296908 | 0.86 | CHKA (0.41) | CHKAHTTKMT2AHRH3FASN | |
| Hydrochloric Acid SCHEMBL2300289 | 0.86 | HTT (0.41) | CHKAHTTKMT2AHRH3FASN | |
| Hydrochloric Acid SCHEMBL2300283 | 0.86 | HTT (0.41) | CHKAHTTKMT2AHRH3FASN | |
| SCHEMBL2027256 | 0.81 | HRH3 (0.35) | CHKAHTTKMT2AHRH3FASN | |
| SCHEMBL2827287 | 0.81 | HRH3 (0.35) | CHKAHTTKMT2AHRH3FASN | |
| SCHEMBL1750077 | 0.73 | PDE7B (0.45) | CHKAHTTHRH3FASNALDH1A1 | |
| SCHEMBL2303903 | 0.73 | PKM (0.45) | KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | claimed |
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | disclosed |