Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681735 | 0.87 | HPGD (0.69) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10373427 | 0.85 | HPGD (0.49) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5643538 | 0.84 | HPGD (0.66) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28524227 | 0.84 | RAB9A (0.64) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28040013 | 0.84 | HPGD (0.73) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2546507 | 0.83 | HPGD (0.71) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27939024 | 0.82 | HPGD (0.70) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11038621 | 0.76 | SCN9A (0.42) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14133157 | 0.76 | POLB (0.73) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14097171 | 0.75 | HPGD (0.69) | HPGDMAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541828-B | Amide imidazole derivative and application thereof | 沈阳药科大学 | 2019-04-02 | — | — | CN | claimed |