SCHEMBL28279366

SCHEMBL28279366

CCOC(=O)C1(OC(=O)c2ccccc2)CCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.49
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
OPRM1 P35372 5/20 0.46
LMNA P02545 1/20 0.45
OPRD1 P41143 3/20 0.45
OPRK1 P41145 3/20 0.45
SLC22A1 O15245 1/20 0.45
SLC6A4 P31645 1/20 0.45
ADRA1A P35348 1/20 0.45
KCNH2 Q12809 1/20 0.45
NPC1 O15118 3/20 0.43
RAB9A P51151 2/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28277976 0.99 SMN1; SMN2 (0.48) SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4
SCHEMBL28279398 0.89 LMNA (0.58) SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4
SCHEMBL28278016 0.87 LMNA (0.56) SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4
SCHEMBL28277979 0.86 LMNA (0.48) SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4
SCHEMBL27851842 0.86 MEN1 (0.50) SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4
SCHEMBL28278001 0.85 LMNA (0.47) SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4
SCHEMBL28278026 0.85 TDP1 (0.49) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL28277994 0.84 TDP1 (0.48) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL31000226 0.80 TSHR (0.52) SMN1; SMN2MEN1KMT2ACYP3A4LMNA
SCHEMBL27859605 0.78 TSHR (0.44) MEN1KMT2ACYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN disclosed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN disclosed