Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10930564 | 0.93 | SIGMAR1 (0.32) | SIGMAR1LMNAHTTSMN1; SMN2TP53 | |
| Sulfuric Acid SCHEMBL28311890 | 0.93 | MEN1 (0.35) | SIGMAR1LMNAHTTSMN1; SMN2TP53 | |
| SCHEMBL28847903 | 0.84 | MAPT (0.35) | SIGMAR1LMNAHTTSMN1; SMN2TP53 | |
| Sulfuric Acid SCHEMBL1746285 | 0.81 | MEN1 (0.44) | SIGMAR1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL28524660 | 0.76 | NPSR1 (0.32) | NPSR1CA1 | |
| Sulfuric Acid SCHEMBL11137352 | 0.76 | NPSR1 (0.46) | HTTTP53MEN1ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL1334876 | 0.76 | NPSR1 (0.46) | HTTTP53MEN1ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL11137355 | 0.76 | NPSR1 (0.46) | HTTTP53MEN1ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL29289482 | 0.76 | NPSR1 (0.46) | HTTTP53MEN1ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL78884 | 0.76 | NPSR1 (0.46) | HTTTP53MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109600993-A | Anti-EGFR antibody drug conjugates | 艾伯维公司 | 2019-04-09 | — | — | CN | disclosed |
| CN-109562169-A | anti-CD 98 antibodies and antibody drug conjugates | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109563167-A | ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |