SCHEMBL28280277

SCHEMBL28280277

N#CC1CO1.c1cc2cc-2c1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 11/20 0.35
PRKACA P17612 2/20 0.35
PRKACG P22612 2/20 0.35
PRKACB P22694 2/20 0.35
NPC1 O15118 1/20 0.33
MEN1 O00255 1/20 0.33
ESR1 P03372 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A3 Q01959 2/20 0.33
SLC6A4 P31645 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
APP P05067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28281370 0.79 DRD2 (0.30)
SCHEMBL7517397 0.75
SCHEMBL5532673 0.75
SCHEMBL7528956 0.75
Propylene Oxide SCHEMBL29238686 0.72 NPC1 (0.41) NPC1MEN1ESR1KMT2ACYP1A2
Phosphine SCHEMBL27544257 0.69
Water SCHEMBL27620318 0.69
SCHEMBL7128135 0.68 TSHR (0.63) SLC6A2SLC6A3SLC6A4
Acetonitrile SCHEMBL28637916 0.68
Nitrogen SCHEMBL3165748 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109503454-A A kind of preparation method of Benzazole compounds 北京化工大学 2019-03-22 CN disclosed