Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323767 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL151988 | 1.00 | — | — | |
| SCHEMBL27978541 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL7863876 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL27907214 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL27907215 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL28982429 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL7872063 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL43151 | 0.97 | — | — | |
| SCHEMBL42455 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109475406-A | Method of inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis | 康斯瓦维有限责任公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109475406-A | Method of inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis | 康斯瓦维有限责任公司 | 2019-03-15 | — | — | CN | disclosed |