SCHEMBL43151

SCHEMBL43151

[CH2]C(Br)CCCCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27907214 0.97 LCK (0.48)
SCHEMBL27978541 0.97 LCK (0.48)
SCHEMBL28280322 0.97 LCK (0.48)
SCHEMBL7863876 0.97 LCK (0.48)
SCHEMBL7872063 0.97 LCK (0.48)
SCHEMBL28982429 0.97 LCK (0.48)
SCHEMBL27907215 0.97 LCK (0.48)
SCHEMBL151988 0.97
SCHEMBL11323767 0.97 LCK (0.48)
SCHEMBL42455 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116710091-A Membrane iron transporter inhibitors for the treatment of myelodysplastic syndrome (MDS) 威佛(国际)股份公司 2023-09-05 CN disclosed
CN-110785417-B Membrane iron transporter inhibitor salts 威佛(国际)股份公司 2023-05-23 CN disclosed
CN-114765955-A Methods and compositions for treating sickle cell disease with an iron transporter inhibitor (VIT-2763) 威佛(国际)股份公司 2022-07-19 CN disclosed
CN-114668761-A Novel ferroportin inhibitors 威佛(国际)股份公司 2022-06-28 CN disclosed
CN-108290878-B Novel ferroportin inhibitors 威佛(国际)股份公司 2022-04-26 CN disclosed
CN-114302882-A Ferroportin inhibitor for treating transfusion-dependent BETA-thalassemia (TDT) 威佛(国际)股份公司 2022-04-08 CN disclosed
CN-114269740-A Ferroportin inhibitors for the prevention and treatment of renal injury 威佛(国际)股份公司 2022-04-01 CN disclosed
CN-110785417-A Membrane ferroportin inhibitor salts 威佛(国际)股份公司 2020-02-11 CN disclosed
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
CN-103492028-B Sulfonaminoquinoline hepcidin antagonists 维福(国际)股份公司 2017-02-08 CN disclosed
EP-0719839-B1 Phthalocyanine compounds and optical recording media comprising them MITSUI CHEMICALS INC (JP) 2001-07-25 EP disclosed
US-6242474-B1 SULFONYLCARBAMOYLALKYLIMIDAZOLE DERIVATIVES; ANTIDIABETIC AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-06-05 US disclosed
US-6166219-A Benzimidazole derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-12-26 US disclosed
CN-1268942-A Sulfonamide compounds and medicinal use thereof FUJISAWA PHARMACEUTICAL CO (JP) 2000-10-04 CN disclosed
EP-1000932-A1 AROMATIC RING DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-05-17 EP disclosed
EP-0995742-A1 SULFONAMIDE COMPOUNDS AND MEDICINAL USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-04-26 EP disclosed
CN-1211238-A Benzimidazole derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1999-03-17 CN disclosed
EP-0882718-A1 BENZIMIDAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-12-09 EP disclosed
US-5693396-A NEAR INFRARED LIGHT ABSORBERS MITSUI TOATSU CHEMICALS, INC. (JP) 1997-12-02 US disclosed
EP-0719839-A2 Phthalocyanine compounds and optical recording media comprising them MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-07-03 EP disclosed