SCHEMBL28280411

SCHEMBL28280411

CCOC(=O)C(C)C(C)=O.[Zr]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
LMNA P02545 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HPGD P15428 1/20 0.46
GAA P10253 2/20 0.40
ALOX15 P16050 1/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
TRPA1 O75762 1/20 0.37
GLO1 Q04760 1/20 0.37
CYP2C19 P33261 2/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.34
PIN1 Q13526 1/20 0.34
MEN1 O00255 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41804 0.97 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10HPGDGAA
SCHEMBL2169170 0.97 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10HPGDGAA
SCHEMBL8800736 0.95 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10HPGDGAA
SCHEMBL17433679 0.95 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10HPGDGAA
Ethane SCHEMBL29036071 0.95 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10HPGDGAA
SCHEMBL5149633 0.91 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10HPGDGAA
SCHEMBL5148157 0.89 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10HPGDGAA
Sulfurous Acid SCHEMBL8754999 0.89 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10HPGDGAA
SCHEMBL5148168 0.89 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10HPGDGAA
SCHEMBL28186389 0.87 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891993-B Low temperature curing 1K basecoat and method for coating a substrate with a 1K basecoat 巴斯夫涂料有限公司 2022-11-22 CN disclosed
CN-110945085-B Low temperature cured coatings formed by polarity-promoted catalyst migration between layers in a two-layer cure mechanism 巴斯夫涂料有限公司 2022-07-12 CN disclosed
CN-109476811-B One-part low temperature cure coating formed via a dual layer cure mechanism 巴斯夫涂料有限公司 2022-02-11 CN disclosed
CN-109476933-B Low temperature cured coatings via a dual layer cure mechanism of a pigmented water-based base layer and a solvent-based top layer 巴斯夫涂料有限公司 2021-10-12 CN disclosed
CN-111433300-A Scratch-resistant and scratch-resistant automotive coatings 巴斯夫涂料有限公司 2020-07-17 CN disclosed
CN-110997836-A Two-component (2K) varnish and method for coating a substrate with a two-component (2K) varnish having an enhanced visual appearance 巴斯夫涂料有限公司 2020-04-10 CN disclosed
CN-110945085-A Low temperature cured coatings formed by polarity-promoted catalyst migration between layers in a dual-layer cure mechanism 巴斯夫涂料有限公司 2020-03-31 CN disclosed
CN-110891993-A Low temperature curing 1K basecoat and method of coating a substrate with a 1K basecoat 巴斯夫涂料有限公司 2020-03-17 CN disclosed
CN-109476811-A One-part low temperature cure coating formed via a dual layer cure mechanism 巴斯夫涂料有限公司 2019-03-15 CN disclosed
CN-109476933-A The low temperature solidification coating formed via the water base base of coloring and the double-deck curing mechanism of solvent base top layer 巴斯夫涂料有限公司 2019-03-15 CN disclosed