Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL28975628 | 0.94 | TSHR (0.50) | TSHRHPGDALOX15ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL27943602 | 0.94 | TSHR (0.50) | TSHRHPGDALOX15ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL1968900 | 0.94 | TSHR (0.50) | TSHRHPGDALOX15ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL19284484 | 0.94 | TSHR (0.50) | TSHRHPGDALOX15ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL28719965 | 0.89 | HCAR2 (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL28099999 | 0.88 | ALOX15 (0.48) | TSHRHPGDALOX15ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL7774420 | 0.88 | TSHR (0.52) | TSHRHPGDALOX15ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL4869923 | 0.86 | TSHR (0.50) | TSHRHPGDALOX15ALDH1A1TP53 | |
| Adamantane SCHEMBL28909417 | 0.84 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL3440788 | 0.84 | TSHR (0.52) | TSHRHPGDALOX15ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109423148-A | A kind of energy-absorbing method based on dynamic aggregation object | 翁秋梅 | 2019-03-05 | — | — | CN | disclosed |