SCHEMBL28280487

SCHEMBL28280487

C=C(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
LMNA P02545 1/20 0.35
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL192824 0.88 THRB (0.32) THRB
SCHEMBL1021902 0.77 THRB (0.50) THRBLMNACA1CA2MMP1
SCHEMBL4426053 0.77 THRB (0.50) THRBLMNACA1CA2MMP1
SCHEMBL6151435 0.76
SCHEMBL24279707 0.75
SCHEMBL31470129 0.74 THRB (0.48) THRBLMNACA1CA2MMP1
SCHEMBL29463706 0.74 THRB (0.48) THRBLMNACA1CA2MMP1
SCHEMBL6704230 0.74 THRB (0.55) THRBLMNACA1CA2MMP1
SCHEMBL31470114 0.74 THRB (0.48) THRBLMNACA1CA2MMP1
SCHEMBL29616992 0.74 THRB (0.48) THRBLMNACA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119261336-A Self-water-absorbing structure water-retaining soil moisture-preserving biodegradable agricultural film and preparation method thereof 江苏智信塑胶科技有限公司 2025-01-07 CN disclosed
CN-109593451-A Bisphenol AF base hydrophobic oleophobic non-isocyanate polyurethane coating and the preparation method and application thereof 华南理工大学 2019-04-09 CN disclosed