Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278650 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1PDE10AL3MBTL1NPC1 | |
| SCHEMBL30771455 | 0.82 | KDM4E (0.68) | ERBB2KDM4EALDH1A1PDE10AL3MBTL1 | |
| SCHEMBL28043991 | 0.82 | KDM4E (0.68) | ERBB2KDM4EALDH1A1PDE10AL3MBTL1 | |
| SCHEMBL28277283 | 0.80 | NOS3 (0.44) | ERBB2KDM4EALDH1A1L3MBTL1RAB9A | |
| SCHEMBL12553478 | 0.80 | ERBB2 (0.66) | ERBB2KDM4EALDH1A1PDE10AL3MBTL1 | |
| SCHEMBL1302744 | 0.78 | ERBB2 (0.64) | ERBB2KDM4EALDH1A1PDE10AL3MBTL1 | |
| SCHEMBL6216319 | 0.77 | ERBB2 (0.62) | ERBB2KDM4EALDH1A1PDE10AL3MBTL1 | |
| SCHEMBL7935213 | 0.72 | CYP3A4 (0.43) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28281957 | 0.71 | KDM4E (0.62) | KDM4EALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL28278673 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422699-A | A kind of synthetic method of alpha-keto amide class compound | 浙江工业大学 | 2019-03-05 | — | — | CN | disclosed |