Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952948 | 0.78 | MAPT (0.47) | KDM4EALDH1A1MAPTCCR1POLB | |
| SCHEMBL3530571 | 0.77 | CYP1A2 (0.55) | KDM4EALDH1A1KMT2ASMN1; SMN2CCR1 | |
| SCHEMBL1562526 | 0.76 | POLB (0.55) | KDM4EALDH1A1MAPTMEN1MPI | |
| SCHEMBL31186680 | 0.76 | POLB (0.55) | KDM4EALDH1A1MAPTMEN1MPI | |
| SCHEMBL24188646 | 0.73 | PSMB5 (0.45) | KDM4EALDH1A1MAPTMEN1MPI | |
| SCHEMBL4101758 | 0.73 | POLB (0.52) | KDM4EALDH1A1MAPTMEN1MPI | |
| SCHEMBL30502987 | 0.73 | POLB (0.52) | KDM4EALDH1A1MAPTMEN1MPI | |
| SCHEMBL10974039 | 0.73 | CYP1A2 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3085387 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10740204 | 0.72 | CYP1A2 (0.57) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422680-B | Synthesis method of N-acetylquinoline-2-amide and derivatives thereof | 浙江工业大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-109422680-A | A kind of synthetic method of N- acetylquinoline -2- amide and its derivative | 浙江工业大学 | 2019-03-05 | — | — | CN | disclosed |