Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085387 | 0.79 | KDM4E (0.67) | MAPTKDM4EPOLBRAB9AL3MBTL1 | |
| SCHEMBL29953541 | 0.78 | ACHE (0.41) | MAPTKDM4ERAB9ACYP1A2CCR1 | |
| SCHEMBL28280669 | 0.78 | KDM4E (0.51) | MAPTKDM4EPOLBRAB9AL3MBTL1 | |
| SCHEMBL2170729 | 0.78 | RAB9A (0.44) | MAPTKDM4EPOLBRAB9AL3MBTL1 | |
| SCHEMBL27260118 | 0.78 | TERT (0.43) | CYP1A2CCR1PDE3BPDE3AALDH1A1 | |
| SCHEMBL28449950 | 0.77 | PDE10A (0.51) | MAPTKDM4EPOLBRAB9APDE3B | |
| SCHEMBL5540363 | 0.75 | CYP1A2 (0.44) | KDM4EPOLBRAB9AL3MBTL1CYP1A2 | |
| SCHEMBL826491 | 0.74 | CYP1A2 (0.57) | POLBCYP1A2BACE1CCR1PDE3B | |
| SCHEMBL6176944 | 0.73 | CCR1 (0.54) | MAPTKDM4ERAB9AL3MBTL1CCR1 | |
| SCHEMBL4818968 | 0.73 | ALDH1A1 (0.62) | MAPTPOLBRAB9AL3MBTL1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |