Methacrylic Acid

Methacrylic Acid

SCHEMBL28280736

C=C(C)C(=O)O.CCCC(=O)OC(C)=O

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FFAR3 O14843 4/20 0.37
HDAC3 O15379 3/20 0.37
HDAC1 Q13547 3/20 0.37
HDAC2 Q92769 3/20 0.37
HDAC8 Q9BY41 3/20 0.37
TSHR P16473 4/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
LMNA P02545 1/20 0.31
THRB P10828 2/20 0.31
PTGS1 P23219 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGGT1B P53609 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL29188780 0.94 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1FFAR3HDAC3
SCHEMBL28837637 0.87 ALDH1A1 (0.61) ALDH1A1HSD17B10TDP1FFAR3HDAC3
Acetic Acid SCHEMBL27480603 0.87 ALDH1A1 (0.67) ALDH1A1HSD17B10TDP1FFAR3HDAC3
SCHEMBL28322960 0.87 ALDH1A1 (0.67) ALDH1A1HSD17B10TDP1FFAR3HDAC3
SCHEMBL24421 0.87
Propionic Acid SCHEMBL9302089 0.85 ALDH1A1 (0.64) ALDH1A1HSD17B10TDP1FFAR3HDAC3
SCHEMBL17159928 0.84 ALDH1A1 (0.70) ALDH1A1HSD17B10TDP1FFAR3HDAC3
SCHEMBL2785670 0.84 ALDH1A1 (0.70) ALDH1A1HSD17B10TDP1FFAR3HDAC3
SCHEMBL5502285 0.84 ALDH1A1 (0.70) ALDH1A1HSD17B10TDP1FFAR3HDAC3
SCHEMBL21753843 0.84 ALDH1A1 (0.70) ALDH1A1HSD17B10TDP1FFAR3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109438637-A A kind of synthesis and its application of polymer 东莞东阳光科研发有限公司 2019-03-08 CN disclosed