Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4814511 | 0.83 | NPSR1 (0.59) | NPSR1KMT2AMAPK10MAPK9 | |
| SCHEMBL5215089 | 0.79 | MAPK9 (0.56) | KMT2AMAPK10MAPK9USP2CYP1A2 | |
| SCHEMBL30599018 | 0.79 | MAPK9 (0.56) | KMT2AMAPK10MAPK9USP2CYP1A2 | |
| SCHEMBL3311451 | 0.78 | CYP1A2 (0.43) | NPSR1KMT2AMAPK10USP2CYP1A2 | |
| SCHEMBL2424040 | 0.78 | DGAT1 (0.62) | NPSR1KMT2ACYP1A2KCNH2ALDH1A1 | |
| SCHEMBL10012834 | 0.78 | NPSR1 (0.44) | NPSR1KMT2AMAPK10USP2CYP1A2 | |
| SCHEMBL30782543 | 0.78 | DGAT1 (0.62) | NPSR1KMT2ACYP1A2KCNH2ALDH1A1 | |
| SCHEMBL3296530 | 0.78 | NPSR1 (0.45) | NPSR1KMT2AMAPK9USP2CYP1A2 | |
| SCHEMBL6323276 | 0.75 | NPSR1 (0.51) | NPSR1KMT2AMAPK10MAPK9KCNH2 | |
| SCHEMBL2275178 | 0.74 | MAPK9 (0.51) | NPSR1KMT2AMAPK10MAPK9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476599-A | Guanidine derivatives and its medical usage | 东丽株式会社 | 2019-03-15 | — | — | CN | disclosed |