Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280983 | 1.00 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL28870396 | 1.00 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL28280956 | 0.80 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1DPP4 | |
| SCHEMBL28280954 | 0.80 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1DPP4 | |
| SCHEMBL28282701 | 0.80 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1DPP4 | |
| SCHEMBL27764382 | 0.78 | OPRL1 (0.41) | OPRM1OPRD1OPRK1OPRL1DPP4 | |
| SCHEMBL4068649 | 0.78 | OPRL1 (0.41) | OPRM1OPRD1OPRK1OPRL1DPP4 | |
| SCHEMBL18751627 | 0.77 | CYP2D6 (0.47) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL3595828 | 0.76 | KMT2A (0.43) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL21334004 | 0.76 | KMT2A (0.43) | OPRM1OPRD1OPRK1OPRL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | disclosed |