SCHEMBL28281002

SCHEMBL28281002

FC(F)(F)Cn1ccc(Cn2cccc2)n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
METTL3 Q86U44 1/20 0.32
KCNH2 Q12809 1/20 0.31
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21034313 0.78 NOTUM (0.33) METTL3HDAC1HDAC7
SCHEMBL18611221 0.77 METTL3 (0.30) METTL3KCNH2
SCHEMBL7996504 0.77 HDAC1 (0.32) METTL3HDAC1HDAC7
SCHEMBL17911156 0.77 METTL3 (0.30) METTL3
SCHEMBL25938500 0.73 CXCR4 (0.41)
SCHEMBL24777116 0.72 METTL3 (0.34) METTL3HDAC1HDAC7
SCHEMBL18169175 0.71 HDAC1 (0.34) METTL3HDAC1HDAC7
SCHEMBL31055718 0.70 METTL3 (0.46) METTL3HDAC1
SCHEMBL29701212 0.70 KDM4E (0.37) METTL3HDAC1HDAC7
SCHEMBL24335765 0.70 FYN (0.35) HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109526219-A Benzsulfamide and its purposes as therapeutic agent 泽农医药公司 2019-03-26 CN disclosed