Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15532009 | 0.98 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8FDPS | |
| Bromide SCHEMBL204550 | 0.98 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8FDPS | |
| SCHEMBL40842 | 0.96 | KMT2A (0.46) | KMT2AALDH1A1POLBTLR8FDPS | |
| Methane SCHEMBL28225457 | 0.94 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8FDPS | |
| Hydrochloric Acid SCHEMBL28021855 | 0.94 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8FDPS | |
| Hydrochloric Acid SCHEMBL204294 | 0.94 | TLR8 (0.44) | KMT2AALDH1A1POLBTLR8FDPS | |
| Hydrochloric Acid SCHEMBL28330230 | 0.94 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8FDPS | |
| Water SCHEMBL1176982 | 0.94 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8FDPS | |
| Iodide SCHEMBL526909 | 0.94 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8FDPS | |
| Fluoride SCHEMBL15156374 | 0.94 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109482230-A | A kind of preparation method of the multicomponent synergistic catalyst for carbon dioxide conversion | 北京工业大学 | 2019-03-19 | — | — | CN | disclosed |