⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133406 | 0.90 | — | — | |
| SCHEMBL4450140 | 0.88 | — | — | |
| SCHEMBL596346 | 0.70 | — | — | |
| SCHEMBL559435 | 0.69 | — | — | |
| SCHEMBL3956046 | 0.69 | — | — | |
| SCHEMBL597428 | 0.65 | — | — | |
| SCHEMBL146951 | 0.65 | — | — | |
| SCHEMBL3157689 | 0.64 | NOS3 (0.32) | — | |
| SCHEMBL6430755 | 0.64 | — | — | |
| SCHEMBL596537 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468953-B1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-05-22 | — | — | EP | claimed |
| US-20240140915-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-05-02 | — | — | US | claimed |
| US-20240101553-A1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2024-03-28 | — | — | US | claimed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | claimed |
| WO-2024010782-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | claimed |
| WO-2023230262-A1 | TRICYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-11-30 | — | — | WO | claimed |
| EP-3844151-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-08-23 | — | — | EP | claimed |
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | claimed |
| US-11390610-B2 | Piperazine derivatives as MAGL inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2022-07-19 | — | — | US | claimed |
| CN-109563043-B | Substituted pyridines as inhibitors of DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-05-31 | — | — | CN | claimed |
| EP-0099121-A2 | Pharmaceutical compositions | Bristol-Myers Company (US) | 1984-01-25 | — | — | EP | claimed |
| EP-0099122-A2 | Compositions comprising pepstatin and an histamine H2-receptor antagonist having an enhanced antiulcer activity | Bristol-Myers Company (US) | 1984-01-25 | — | — | EP | claimed |
| EP-0038636-B1 | SULFONAMIDE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-01-11 | — | — | EP | claimed |
| US-4394508-A | ANTIULCER AND ANTISECRETORY AGENTS; HISTAMINE ANTAGONIST | BRISTOL-MYERS COMPANY (US) | 1983-07-19 | — | — | US | claimed |
| US-4380639-A | ANTIULCER AND ANTISECRETORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | claimed |
| US-4380638-A | ANTIULCER AND ANTISECRETORY AGENTS; DERIVATIVES OF 3-AMINO-4-HET-A | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | claimed |
| US-4321081-A | Ortho-(trifluoromethylsulfonamido)benzamides as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-23 | — | — | US | claimed |
| EP-0038636-A2 | Sulfonamide derivatives, compositions containing them and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-28 | — | — | EP | claimed |
| US-4263039-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-04-21 | — | — | US | claimed |
| US-4157392-A | HYPOTENSIVE AGENTS, ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS AND NERVOUS SYSTEM EFFECTS | DIAMOND SHAMROCK CORPORATION (US) | 1979-06-05 | — | — | US | claimed |