Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28282002

C1CCOC1.CCC1CCCCC1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
ALDH1A1 P00352 2/20 0.40
SHBG P04278 1/20 0.32
ACHE P22303 1/20 0.31
CHRM5 P08912 2/20 0.31
ADRA2C P18825 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
HSD11B1 P28845 1/20 0.31
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27694260 0.95 CYP1A2 (0.38) CYP1A2ALDH1A1SHBG
SCHEMBL27694261 0.95 CYP1A2 (0.38) CYP1A2ALDH1A1SHBG
SCHEMBL27675771 0.95 CYP1A2 (0.38) CYP1A2ALDH1A1SHBG
SCHEMBL27675767 0.95 CYP1A2 (0.38) CYP1A2ALDH1A1SHBG
SCHEMBL28459300 0.95 CYP1A2 (0.38) CYP1A2ALDH1A1SHBG
SCHEMBL23812619 0.95 CYP1A2 (0.38) CYP1A2ALDH1A1SHBG
SCHEMBL28184251 0.93 ALDH1A1 (0.38) CYP1A2ALDH1A1
SCHEMBL19093842 0.90 ALDH1A1 (0.37) CYP1A2ALDH1A1
SCHEMBL12993553 0.85
SCHEMBL4576671 0.84 CYP1A2 (0.52) CYP1A2SHBGACHECHRM5ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790418-A Surface conditioner, coating composition containing the same, and method for forming coating film 关西涂料株式会社 2019-05-21 CN disclosed
CN-109414021-A Antibacterial composition, antibacterial film, substrate with antibacterial film, method for producing antibacterial film, and method for producing substrate with antibacterial film 富士胶片株式会社 2019-03-01 CN disclosed