SCHEMBL28282138

SCHEMBL28282138

CCCN1CC(c2ccc(S(C)(=O)=O)cc2)=C(c2ccc(CN)cc2)C1=O

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 18/20 0.79
PTGS1 P23219 17/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5850192 0.86 PTGS1 (0.78) PTGS2PTGS1
Imrecoxib SCHEMBL3034253 0.86 PTGS2 (0.76) PTGS2PTGS1
SCHEMBL3034257 0.86 PTGS2 (0.76) PTGS2PTGS1
SCHEMBL5848742 0.85 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL5850087 0.85 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL5848436 0.85 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL5848449 0.85 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL5849700 0.81 PTGS2 (0.65) PTGS2PTGS1
SCHEMBL28290157 0.81 PTGS2 (0.52) PTGS2PTGS1
SCHEMBL5847947 0.81 PTGS2 (0.64) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553563-A A kind of azoles and preparation method thereof, purposes 江苏恒瑞医药股份有限公司 2019-04-02 CN claimed