SCHEMBL28282500

SCHEMBL28282500

CC(C)(C)NC1CCN(c2cc(C#N)nc3ccccc23)CC1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 5/20 0.41
NSD2 O96028 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ACVR1 Q04771 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28282562 0.99 NCF1 (0.41) NCF1NSD2ADRB2ADRB1ACVR1
SCHEMBL28284091 0.82 NCF1 (0.45) NCF1ADRB2ADRB1
SCHEMBL16096541 0.81 KDM4E (0.61) NCF1
Hydrochloric Acid SCHEMBL16101548 0.81 KDM4E (0.60) NCF1
Hydrochloric Acid SCHEMBL16096749 0.81 KDM4E (0.60) NCF1
SCHEMBL14046595 0.78 NCF1 (0.64) NCF1ADRB2ADRB1
SCHEMBL16097530 0.78 KDM4E (0.53)
SCHEMBL16098517 0.78 ACP1 (0.52)
Hydrochloric Acid SCHEMBL16098155 0.77 KDM4E (0.52)
SCHEMBL21796407 0.77 HRH4 (0.50) NCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415343-A For treating substituted 2,4- diamino-quinoline of proliferative diseases 基因科学医药公司 2019-03-01 CN disclosed