SCHEMBL28282959

SCHEMBL28282959

CCCCCCCCCCC1(N)C=CC1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.35
DNM1 Q05193 9/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
EPHX1 P07099 1/20 0.33
MMP2 P08253 2/20 0.32
MMP9 P14780 2/20 0.32
MMP3 P08254 1/20 0.32
CYP19A1 P11511 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28282901 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL27842328 0.75 HTR2A (0.33)
SCHEMBL28053367 0.70 TSHR (0.40) TSHRTHRBDNM1ALDH1A1
SCHEMBL21417322 0.67 TSHR (0.42) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL24892998 0.64 DNM1 (0.40) TSHRTHRBDNM1
SCHEMBL2146878 0.63 TSHR (0.41) TSHRTHRBDNM1ALDH1A1MMP2
Heptane SCHEMBL8194072 0.59
Methylamine SCHEMBL6912272 0.59 TSHR (0.80) TSHRTHRBDNM1MEN1KMT2A
Tetradecane SCHEMBL11863474 0.59 TSHR (0.80) TSHRTHRBDNM1MEN1KMT2A
Hexadecane SCHEMBL11859645 0.59 TSHR (0.80) TSHRTHRBDNM1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167977-A Conjugated diene polymer, conjugated diene polymer composition and tire 日本弹性体株式会社 2019-08-23 CN disclosed
CN-109384982-A Modified conjugated diene polymer composition and tire 旭化成株式会社 2019-02-26 CN disclosed