Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 18/20 | 0.66 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639023 | 0.82 | HCAR3 (0.62) | HCAR3HCAR2L3MBTL1 | |
| SCHEMBL28097209 | 0.81 | HCAR3 (0.50) | HCAR3 | |
| SCHEMBL7230169 | 0.81 | HCAR3 (0.73) | HCAR3HCAR2 | |
| SCHEMBL840255 | 0.80 | ACACB (0.46) | HCAR3L3MBTL1 | |
| SCHEMBL31058294 | 0.80 | HCAR3 (0.71) | HCAR3HCAR2 | |
| SCHEMBL3562313 | 0.80 | HCAR3 (0.71) | HCAR3HCAR2 | |
| SCHEMBL186474 | 0.80 | HCAR3 (1.00) | HCAR3HCAR2 | |
| SCHEMBL28284471 | 0.78 | HCAR3 (0.60) | HCAR3HCAR2 | |
| SCHEMBL18193683 | 0.78 | HCAR3 (0.74) | HCAR3HCAR2 | |
| SCHEMBL14805817 | 0.78 | HCAR3 (0.68) | HCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061967-B | The nicotinamide compounds replaced through heteroaryl | 百时美施贵宝公司 | 2019-04-19 | — | — | CN | disclosed |