Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28381906 | 0.81 | CTSL (0.73) | CTSLKDM4EALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL28887932 | 0.81 | CTSL (0.73) | CTSLKDM4EALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL6337478 | 0.81 | CTSL (1.00) | CTSLKDM4EALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL18477265 | 0.79 | CTSL (0.53) | CTSLMEN1GAAKMT2AKDM4E | |
| SCHEMBL28381876 | 0.78 | CTSL (0.52) | CTSLMEN1GAAKMT2AKDM4E | |
| SCHEMBL28384974 | 0.78 | CTSL (0.52) | CTSLMEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL28383150 | 0.78 | CTSL (0.52) | CTSLMEN1GAAKMT2AKDM4E | |
| SCHEMBL28383046 | 0.78 | CTSL (0.58) | CTSLMEN1GAAKMT2AKDM4E | |
| SCHEMBL28388654 | 0.78 | CTSL (0.58) | CTSLGAAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL28387201 | 0.77 | CTSL (0.64) | CTSLKDM4EALDH1A1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503478-A | 2,3- dihydro -1H- quinolin-4-one thiosemicarbazone derivative and its preparation method and application | 岭南师范学院 | 2019-03-22 | — | — | CN | claimed |
| CN-109503478-B | 2, 3-dihydro-1H-quinoline-4-ketone thiosemicarbazone derivative and preparation method and application thereof | 岭南师范学院 | 2020-04-24 | — | — | CN | disclosed |
| CN-109503478-A | 2,3- dihydro -1H- quinolin-4-one thiosemicarbazone derivative and its preparation method and application | 岭南师范学院 | 2019-03-22 | — | — | CN | disclosed |
| CN-109503478-A | 2,3- dihydro -1H- quinolin-4-one thiosemicarbazone derivative and its preparation method and application | 岭南师范学院 | 2019-03-22 | — | — | CN | disclosed |
| CN-109503478-A | 2,3- dihydro -1H- quinolin-4-one thiosemicarbazone derivative and its preparation method and application | 岭南师范学院 | 2019-03-22 | — | — | CN | disclosed |