SCHEMBL28284656

SCHEMBL28284656

C=Cc1ccc(-c2cccc(-c3ccccc3)c2-c2ccc(C=C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 1/20 0.50
HNF4A P41235 1/20 0.36
GRM1 Q13255 1/20 0.36
ENPP1 P22413 1/20 0.36
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAPK1 P28482 1/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC4 P56524 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
DRD1 P21728 1/20 0.35
DAPK3 O43293 1/20 0.35
JAK2 O60674 1/20 0.35
ABL1 P00519 1/20 0.35
NTRK1 P04629 1/20 0.35
FYN P06241 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16180732 0.94 ALDH1A1 (0.50) ALDH1A1TSHRGRM1ENPP1HDAC2
SCHEMBL8759106 0.87 ALDH1A1 (0.59) ALDH1A1TSHRGRM1HSD17B10HPGD
SCHEMBL28928500 0.85 ALDH1A1 (0.56) ALDH1A1TSHRGRM1HSD17B10HPGD
SCHEMBL14877347 0.85 ALDH1A1 (0.62) ALDH1A1TSHRHSD17B10BCL2L1MAPK1
SCHEMBL16174757 0.82 ALDH1A1 (0.42) ALDH1A1TSHRHSD17B10HPGDHDAC2
SCHEMBL17747939 0.82 ALDH1A1 (0.42) ALDH1A1TSHRDRD1DAPK3JAK2
SCHEMBL5880675 0.82 ALDH1A1 (0.43) ALDH1A1TSHRGRM1ENPP1HSD17B10
Styrene SCHEMBL11560726 0.81 ALDH1A1 (0.70) ALDH1A1TSHRGRM1HSD17B10HPGD
SCHEMBL15056 0.80 ALDH1A1 (0.68) ALDH1A1TSHRHSD17B10BCL2L1MAPK1
SCHEMBL447854 0.80 ALDH1A1 (0.68) ALDH1A1TSHRHSD17B10BCL2L1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109698210-A Promote the radioscopic image sensor of middle layer and soft sintering perovskite active layer containing adherency 西门子保健有限责任公司 2019-04-30 CN disclosed
CN-109494307-A Light emitting diode with quantum dots and quantum dot including the light emitting diode with quantum dots show equipment 乐金显示有限公司 2019-03-19 CN disclosed