Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PLEC | Q15149 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740982 | 0.80 | PTGER4 (0.61) | HDAC6ALDH1A1CYP3A4SMN1; SMN2PTGER4 | |
| SCHEMBL2722710 | 0.79 | ALDH1A1 (0.56) | HDAC6ALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL124591 | 0.77 | HDAC6 (0.71) | HDAC6ALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL3637289 | 0.76 | HDAC6 (0.59) | HDAC6ALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL19540834 | 0.74 | GAA (0.61) | ALDH1A1CYP3A4TDP1SMN1; SMN2KDM4E | |
| SCHEMBL10249397 | 0.74 | HDAC6 (0.50) | HDAC6ALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL1497919 | 0.74 | HDAC6 (0.58) | HDAC6ALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL7137884 | 0.73 | HDAC6 (0.65) | HDAC6CYP3A4TDP1ALOX15THRB | |
| SCHEMBL20810715 | 0.73 | HDAC6 (0.52) | HDAC6ALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL9759453 | 0.72 | HDAC6 (0.55) | HDAC6ALDH1A1CYP3A4PTGER4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109481427-A | Application of the compound FC-99 in preparation prevention or treatment acute hepatic failure drug | 南京大学 | 2019-03-19 | — | — | CN | disclosed |