SCHEMBL2828512

SCHEMBL2828512

O=C1OC(=O)c2c(Oc3ccccc3)cccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ADORA2A P29274 1/20 0.44
LMNA P02545 2/20 0.43
KMT2A Q03164 2/20 0.43
HKDC1 Q2TB90 2/20 0.43
TP53 P04637 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
XBP1 P17861 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
BRD4 O60885 3/20 0.42
GAA P10253 1/20 0.42
ELANE P08246 1/20 0.41
PTGS2 P35354 1/20 0.41
STK10 O94804 1/20 0.40
SLK Q9H2G2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889793 0.93 TDP1 (0.43) ALOX15TDP1ADORA2ALMNAKMT2A
SCHEMBL31104976 0.93 TDP1 (0.43) ALOX15TDP1ADORA2ALMNAKMT2A
SCHEMBL30930078 0.91 TDP1 (0.41) ALOX15TDP1ADORA2ALMNAKMT2A
SCHEMBL24946583 0.91 TDP1 (0.41) ALOX15TDP1ADORA2ALMNAKMT2A
SCHEMBL31105268 0.89 TDP1 (0.40) ALOX15TDP1ADORA2ALMNAKMT2A
SCHEMBL23776321 0.89 TDP1 (0.40) ALOX15TDP1ADORA2ALMNAKMT2A
SCHEMBL31019584 0.88 TDP1 (0.39) ALOX15TDP1ADORA2ALMNAKMT2A
SCHEMBL22304634 0.88 TDP1 (0.39) ALOX15TDP1ADORA2ALMNAKMT2A
SCHEMBL15400203 0.87 TDP1 (0.50) ALOX15TDP1KMT2APOLBMAPT
SCHEMBL261809 0.87 TDP1 (0.48) ALOX15TDP1LMNAKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4281100-A Injection moldable polyetherimide oligomers and method for making GENERAL ELECTRIC COMPANY (US) 1981-07-28 US claimed
JP-1128977-A None JP disclosed
CN-109153786-B Method for preparing polyetherimide 沙特基础工业全球技术有限公司 2021-03-30 CN disclosed
CN-108368262-B Method for preparing polyetherimide 沙特基础工业全球技术有限公司 2021-03-23 CN disclosed
US-10829594-B2 Method of making polyetherimide SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-11-10 US disclosed
US-10793675-B2 Method of making polyetherimide SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-10-06 US disclosed
US-20190292318-A1 METHOD OF MAKING POLYETHERIMIDE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-09-26 US disclosed
EP-3464421-A1 METHOD OF MAKING POLYETHERIMIDE SABIC Global Technologies B.V. (NL) 2019-04-10 EP disclosed
US-20190023845-A1 METHOD OF MAKING POLYETHERIMIDE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-01-24 US disclosed
EP-3397673-A1 METHOD OF MAKING POLYETHERIMIDE SABIC Global Technologies B.V. (NL) 2018-11-07 EP disclosed
JP-H01128977-A PRODUCTION OF PHENOXY PHTHALIC ANHYDRIDE OCCIDENTAL CHEM CORP 1989-05-22 JP disclosed
US-4827000-A REACTION OF FLUOROPHTHALIC ANHYDRIDE WITH A PHENOL OCCIDENTAL CHEMICAL CORPORATION (US) 1989-05-02 US disclosed
US-4827000-A REACTION OF FLUOROPHTHALIC ANHYDRIDE WITH A PHENOL OCCIDENTAL CHEMICAL CORPORATION (US) 1989-05-02 US disclosed
US-4827000-A REACTION OF FLUOROPHTHALIC ANHYDRIDE WITH A PHENOL OCCIDENTAL CHEMICAL CORPORATION (US) 1989-05-02 US disclosed
EP-0308863-A2 Process for the preparation of phenoxy phthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1989-03-29 EP disclosed
EP-0308863-A2 Process for the preparation of phenoxy phthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1989-03-29 EP disclosed
EP-0308863-A2 Process for the preparation of phenoxy phthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1989-03-29 EP disclosed
EP-0145078-B1 DIPHENYL ETHER HERBICIDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-10-12 EP disclosed
EP-0145078-A2 Diphenyl ether herbicides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-06-19 EP disclosed
US-4281100-A Injection moldable polyetherimide oligomers and method for making GENERAL ELECTRIC COMPANY (US) 1981-07-28 US disclosed