SCHEMBL28285293

SCHEMBL28285293

Nc1cc(C(F)(c2ccc(Nc3ccccc3)c(N)c2)C(F)(F)C(F)(F)F)ccc1Nc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.72
GAA P10253 11/20 0.72
KDM4E B2RXH2 9/20 0.72
ALDH1A1 P00352 8/20 0.72
MEN1 O00255 5/20 0.72
KMT2A Q03164 5/20 0.72
GFER P55789 4/20 0.72
L3MBTL1 Q9Y468 3/20 0.72
HPGD P15428 3/20 0.48
HSD17B10 Q99714 2/20 0.48
THRB P10828 1/20 0.48
LMNA P02545 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2D6 P10635 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
RAB9A P51151 1/20 0.47
HTT P42858 3/20 0.42
TDP1 Q9NUW8 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29708495 0.84 GAA (0.77) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL376200 0.84 GAA (0.77) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL29540467 0.84 GAA (0.77) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL29049650 0.84 GAA (0.52) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL25533205 0.82 GAA (0.72) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL28285295 0.81 GAA (0.70) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL28285299 0.79 GAA (0.68) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL28238458 0.78 KDM4E (0.44) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL23057879 0.78 GAA (0.67) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL2631206 0.78 GAA (0.71) MAPTGAAKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118064069-A Multilayer bonding material and preparation method and application thereof 上海熹贾精密技术有限公司 2024-05-24 CN disclosed
CN-117989323-A Sealing assembly and preparation method thereof 上海熹贾精密技术有限公司 2024-05-07 CN disclosed
CN-114364710-B Method and composition for producing perfluoroelastomer 大金工业株式会社 2024-02-09 CN disclosed
CN-117321105-A Method for producing fluorine-containing polymer, method for producing polytetrafluoroethylene, and composition 大金工业株式会社 2023-12-29 CN disclosed
CN-117255779-A Bisdiaminophenyl compound, crosslinking agent, composition and molded article 大金工业株式会社 2023-12-19 CN disclosed
CN-112543788-B Fluoropolymer-containing composition and molded article 大金工业株式会社 2023-10-24 CN disclosed
CN-116547317-A Method for producing perfluoroelastomer aqueous dispersion, composition, crosslinkable composition, and crosslinked product 大金工业株式会社 2023-08-04 CN disclosed
CN-116507651-A Fluoropolymer, aqueous dispersion, composition and crosslinked product 大金工业株式会社 2023-07-28 CN disclosed
CN-113825795-B Fluoroelastomer composition and article 大金工业株式会社 2023-07-18 CN disclosed
CN-113195625-B Composition and molded article 国立大学法人秋田大学 2023-05-02 CN disclosed
CN-112513175-A Fluoropolymer-containing composition and molded article 大金工业株式会社 2021-03-16 CN disclosed
CN-111757906-A Curable fluoroelastomer compositions 3M创新有限公司 2020-10-09 CN disclosed
CN-111757908-A Curable fluoroelastomer compositions 3M创新有限公司 2020-10-09 CN disclosed
CN-111742004-A Blends of crosslinking agents for fluoroelastomers 3M创新有限公司 2020-10-02 CN disclosed
CN-107636066-B Composition containing fluoropolymer and molded article 大金工业株式会社 2020-06-05 CN disclosed
CN-111212874-A Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2020-05-29 CN disclosed
CN-110709465-A Fluorine-containing elastomer composition and molded article thereof 国立大学法人东京工业大学 2020-01-17 CN disclosed
CN-109996832-A Polymer, composition and molded product 大金工业株式会社 2019-07-09 CN disclosed
CN-109578581-A Seal comprising metal cover, method of making same, and method of using same 台湾积体电路制造股份有限公司 2019-04-05 CN disclosed
CN-109476896-A Composition and molded product 国立大学法人秋田大学 2019-03-15 CN disclosed