SCHEMBL376200

SCHEMBL376200

Nc1cc(C(c2ccc(Nc3ccccc3)c(N)c2)(C(F)(F)F)C(F)(F)F)ccc1Nc1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 12/20 0.77
MAPT P10636 12/20 0.77
KDM4E B2RXH2 10/20 0.77
ALDH1A1 P00352 8/20 0.77
MEN1 O00255 6/20 0.77
KMT2A Q03164 6/20 0.77
GFER P55789 5/20 0.77
L3MBTL1 Q9Y468 3/20 0.77
HPGD P15428 3/20 0.50
LMNA P02545 3/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2D6 P10635 1/20 0.50
THRB P10828 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.49
RAB9A P51151 1/20 0.49
HTT P42858 3/20 0.44
TDP1 Q9NUW8 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29540467 1.00 GAA (0.77) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL29708495 1.00 GAA (0.77) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL23057879 0.93 GAA (0.67) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL10068514 0.92 GAA (0.65) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL25533949 0.90 GAA (0.63) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL9575352 0.87 GAA (0.59) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL25535335 0.87 GAA (0.59) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL23514965 0.85 GAA (0.56) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL25533205 0.84 GAA (0.72) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL28285293 0.84 MAPT (0.72) GAAMAPTKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583957-B2 Fluoropolymer-containing composition and molded article DAIKIN INDUSTRIES, LTD. (JP) 2026-03-24 US disclosed
US-20260071012-A1 METHOD FOR PRODUCING FLUOROPOLYMER, METHOD FOR PRODUCING POLYTETRAFLUOROETHYLENE, METHOD FOR PRODUCING PERFLUOROELASTOMER, AND COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2026-03-12 US disclosed
US-20260062505-A1 METHOD FOR PRODUCING FLUOROPOLYMER DAIKIN INDUSTRIES, LTD. (JP) 2026-03-05 US disclosed
EP-4253432-B1 FLUOROPOLYMER, AQUEOUS LIQUID DISPERSION, COMPOSITION, AND CROSSLINKED PRODUCT DAIKIN IND LTD (JP) 2026-02-25 EP disclosed
US-12503527-B2 Method for producing fluoropolymer, method for producing polytetrafluoroethylene, method for producing perfluoroelastomer, and composition DAIKIN INDUSTRIES, LTD. (JP) 2025-12-23 US disclosed
US-12492271-B2 Method for producing fluoropolymer DAIKIN INDUSTRIES, LTD. (JP) 2025-12-09 US disclosed
EP-4655344-A1 FLUOROPOLYMER COMPOSITIONS AND ARTICLES MADE THEREFROM Dupont Specialty Products USA, LLC (US) 2025-12-03 EP disclosed
US-20250340727-A1 POLYMER BLEND, CROSSLINKABLE COMPOSITION AND ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-11-06 US disclosed
US-12448466-B2 Method for producing perfluoroelastomer and composition DAIKIN INDUSTRIES, LTD. (JP) 2025-10-21 US disclosed
EP-4632002-A1 POLYMER BLEND, CROSSLINKABLE COMPOSITION, AND ARTICLE Daikin Industries, Ltd. (JP) 2025-10-15 EP disclosed
US-20050070637-A1 Crosslinkable elastomer composition and formed product comprising the same DAIKIN INDUSTRIES, LTD. (JP) 2005-03-31 US disclosed
US-20050020748-A1 Molded article of a crosslinked fluorine-containing elastomer containing an inorganic filler; heat resistance for use at high temperature, resistance to high density plasma; use sealing semiconductor manufacturing equipment DAIKIN INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1464671-A1 ELASTOMER FORMED PRODUCT Daikin Industries, Ltd. (JP) 2004-10-06 EP disclosed
EP-1464676-A1 CROSSLINKABLE ELASTOMER COMPOSITION AND FORMED PRODUCT COMPRISING THE SAME Daikin Industries, Ltd. (JP) 2004-10-06 EP disclosed
EP-1245635-A1 FLUOROELASTOMER COMPOSITION FOR CROSSLINKING Daikin Industries, Ltd. (JP) 2002-10-02 EP disclosed
EP-0278414-B1 PROCESS FOR THE PREPARATION OF REACTION PRODUCTS OF 2,2-BIS (4-HYDROXYPHENYL) HEXAFLUOROPROPANE, AND THE DERIVATIVES OBTAINED HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-11 EP disclosed
US-5028728-A Process for the preparation of reaction products of 2,2-bis-(4-hydroxphenyl)-hexafluoropropane and new derivatives of this type HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-02 US disclosed
EP-0278414-A2 Process for the preparation of reaction products of 2,2-bis (4-hydroxyphenyl) hexafluoropropane, and the derivatives obtained HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-17 EP disclosed
US-4587315-A Diethynylated phenylbenzimidazole compounds HUGHES AIRCRAFT COMPANY (US) 1986-05-06 US disclosed
US-4537974-A Diethynylated phenylbenzimidazole compounds HUGHES AIRCRAFT COMPANY (US) 1985-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062505-A1 METHOD FOR PRODUCING FLUOROPOLYMER F9, AFF1, FGB GAA 4231/4885MAPT 1258/4885KDM4E 4116/4885
US-12583957-B2 Fluoropolymer-containing composition and molded article AOC2, AOC1, AOC3 GAA 4653/4885MAPT 3337/4885KDM4E 3114/4885
US-20260071012-A1 METHOD FOR PRODUCING FLUOROPOLYMER, METHOD FOR PRODUCING POLYTETRAFLUOROETHYLENE, METHOD FOR PRODUCING PERFLUOROELASTOMER, AND COMPOSITION F7, PF4, PFN1 GAA 4876/4885MAPT 3675/4885KDM4E 1769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.