Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406737 | 0.98 | MAPT (0.59) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| Methane SCHEMBL28285604 | 0.97 | MAPT (0.58) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL28282523 | 0.85 | MAPT (0.57) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL2783058 | 0.83 | OGFRL1 (0.56) | MAPTRXFP1TP53KDM4EALDH1A1 | |
| SCHEMBL28434021 | 0.83 | MAPT (0.51) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL29724622 | 0.81 | ALDH1A1 (0.59) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL2783065 | 0.81 | ALDH1A1 (0.59) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL35211812 | 0.80 | MAPT (0.56) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL5208264 | 0.80 | MAPT (0.56) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL28402717 | 0.80 | MAPK1 (0.72) | MAPTTP53KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535086-A | A kind of synthetic method of -2 C-3 carboxylate compounds of (1H) -one of quinoxaline | 湖南科技学院 | 2019-03-29 | — | — | CN | disclosed |