Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Thiourea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL7022110 | 0.95 | — | — | |
| Thiourea SCHEMBL360269 | 0.95 | — | — | |
| Thiourea SCHEMBL2811652 | 0.95 | HRH4 (0.35) | — | |
| Thiourea SCHEMBL4915488 | 0.95 | HRH4 (0.35) | — | |
| Thiourea SCHEMBL4919729 | 0.95 | — | — | |
| Thiourea SCHEMBL27504770 | 0.90 | — | — | |
| Thiourea SCHEMBL9370706 | 0.90 | — | — | |
| Thiourea SCHEMBL7022109 | 0.90 | — | — | |
| Thiourea SCHEMBL28271193 | 0.89 | — | — | |
| Thiourea SCHEMBL50650 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574944-A | Isoxazoline derivative and its application in agricultural | 东莞东阳光科研发有限公司 | 2019-04-05 | — | — | CN | disclosed |