Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Thiourea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL4915488 | 1.00 | HRH4 (0.35) | — | |
| Thiourea SCHEMBL4919729 | 1.00 | — | — | |
| Thiourea SCHEMBL2811652 | 1.00 | HRH4 (0.35) | — | |
| Thiourea SCHEMBL28286014 | 0.95 | — | — | |
| Thiourea SCHEMBL28271193 | 0.94 | — | — | |
| Thiourea SCHEMBL50650 | 0.94 | — | — | |
| Thiourea SCHEMBL1395770 | 0.94 | NOS2 (0.36) | — | |
| Thiourea SCHEMBL27672592 | 0.91 | — | — | |
| Thiourea SCHEMBL7022110 | 0.91 | — | — | |
| Thiourea SCHEMBL15375651 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115926563-B | Preparation method and application of high-strength composite antibacterial aluminum foil coating | 万华化学集团股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-115926563-A | Preparation method and application of high-strength composite antibacterial aluminum foil coating | 万华化学集团股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-106729700-B | Surface guanidine group modified nano adjuvant material and preparation method and application thereof | 天津千顺科技有限公司 | 2020-07-07 | — | — | CN | claimed |
| CN-105492381-B | Modified sulphur, preparation method, its preparation facilities with and application thereof | 韩国科学技术研究院 | 2019-03-08 | — | — | CN | claimed |
| CN-103980330-B | Preparation method of isothiourea dihydrobromide | 济南圣泉唐和唐生物科技有限公司 | 2017-02-01 | — | — | CN | claimed |
| CN-103896859-B | The technique of synthesizing cytimidine | 浙江先锋科技股份有限公司 | 2016-08-17 | — | — | CN | claimed |
| CN-105492381-A | Modified sulfur, method for preparing same, apparatus for preparing same, and use thereof | KOREA INST SCI & TECH | 2016-04-13 | — | — | CN | claimed |
| CN-102659853-B | Method for purifying substances by utilizing chromatographic column | Ji'nan Healtang Biotechnology Co., Ltd. (CN) | 2014-10-08 | — | — | CN | claimed |
| CN-103896859-A | Process for synthesizing cytosine | ZHEJIANG XIANFENG TECHNOLOGIES CO LTD | 2014-07-02 | — | — | CN | claimed |
| CN-102659853-A | Method for purifying substances by utilizing chromatographic column | JINAN SHENGQUANTANG HETANG BIO TECHNOLOGY CO LTD | 2012-09-12 | — | — | CN | claimed |
| US-5464624-A | Method for loading a delivery system for a chemical repellant composition | ISBELL ARTHUR F (US) | 1995-11-07 | — | — | US | claimed |
| US-4338465-A | Synthesized scent | MEILLER RESEARCH, INC. (US) | 1982-07-06 | — | — | US | claimed |
| US-4259103-A | ADSORPTION ON SUBSTRATE BY ION EXCHANGE | DOW CORNING CORPORATION (US) | 1981-03-31 | — | — | US | claimed |
| US-4213875-A | Synthesized scent | MEILLER RESEARCH, INC. (US) | 1980-07-22 | — | — | US | claimed |
| CN-114773282-B | Preparation method of 3-tert-butyl-6-ethylthio-1, 3, 5-triazine-2, 4 (1H, 3H) -dione | 杭州布朗生物医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117677401-A | Gariferson for use in a method of preventing or treating a respiratory viral infection | 索米克生物技术有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117500799-A | Substituted fused azines as KRAS G12D inhibitors | 伊莱利利公司 | 2024-02-02 | — | — | CN | disclosed |
| US-4213875-A | Synthesized scent | MEILLER RESEARCH, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4189471-A | IN VACCINES | MERCK & CO., INC. (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0007277-A2 | New glycolipid compound useful as immunologic adjuvant and its preparation | MERCK & CO. INC. (US) | 1980-01-23 | — | — | EP | disclosed |