Butadiene

Butadiene

SCHEMBL28286276

C=C(C)C#N.C=CC=C.CC=CC

nearest known ligand 0.61

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL28152965 0.92 TDP1 (0.65) TDP1ALDH1A1TP53TSHR
Butadiene SCHEMBL2133137 0.91
Propene SCHEMBL28139792 0.85
Acrylonitrile SCHEMBL11808927 0.83 TDP1 (0.61) TDP1ALDH1A1TP53TSHR
Butadiene SCHEMBL27568645 0.83 TDP1 (0.61) TDP1ALDH1A1TP53TSHR
Propene SCHEMBL27443316 0.82 TDP1 (0.69) TDP1ALDH1A1TP53TSHR
SCHEMBL28215697 0.79
Butadiene SCHEMBL11805947 0.79 TDP1 (0.55) TDP1ALDH1A1TP53TSHR
SCHEMBL14868 0.78
SCHEMBL9859678 0.78 TDP1 (1.00) TDP1ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689711-A Composition 电化株式会社 2019-04-26 CN disclosed