Butadiene

Butadiene

SCHEMBL27568645

C=C(C)C#N.C=CC(=C)C.C=CC=C

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
ALDH1A1 P00352 2/20 0.56
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5547539 0.94 TDP1 (0.69) TDP1ALDH1A1TP53TSHR
Butadiene SCHEMBL2133137 0.91
Butadiene SCHEMBL28152965 0.86 TDP1 (0.65) TDP1ALDH1A1TP53TSHR
Acrylonitrile SCHEMBL11808927 0.83 TDP1 (0.61) TDP1ALDH1A1TP53TSHR
Butadiene SCHEMBL28286276 0.83 TDP1 (0.61) TDP1ALDH1A1TP53TSHR
Acrylonitrile SCHEMBL1408524 0.83 ALDH1A1 (0.56) TDP1ALDH1A1TP53TSHR
Acrylic Acid SCHEMBL28067453 0.82 TDP1 (0.52) TDP1ALDH1A1TP53TSHR
Butadiene SCHEMBL23535052 0.82 ALDH1A1 (0.83) ALDH1A1TP53TSHR
Butadiene SCHEMBL10325977 0.82 ALDH1A1 (0.83) ALDH1A1TP53TSHR
Butadiene SCHEMBL2784523 0.82 ALDH1A1 (0.83) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1310959-C Method for hydrogenating conjugated diene polymer, hydrogenation catalyst system, and basic conjugated diene polymer composition NIPPON ZEON CO (JP) 2007-04-18 CN disclosed
CN-1589283-A Method of hydrogenating conjugated diene polymer, hydrogenation catalyst system, and composition of basic conjugated diene polymer NIPPON ZEON CO (JP) 2005-03-02 CN disclosed