SCHEMBL28286403

SCHEMBL28286403

CCOC(C)N(O)c1nc(N)nc(N)n1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.30
CCNB1 P14635 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30
CCNA1 P78396 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4164441 0.74 LMNA (0.34)
SCHEMBL10493356 0.72 LMNA (0.60) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL6723865 0.70 MAPT (0.39) CDK1CCNB1CDK2
SCHEMBL4163976 0.70 MAPT (0.32)
SCHEMBL4667837 0.70 MAPT (0.32)
SCHEMBL28464727 0.68
SCHEMBL3845577 0.66 MAPT (0.43) CDK1CCNB1CDK2
SCHEMBL28180231 0.64 MAPT (0.33)
SCHEMBL22264550 0.64
SCHEMBL17697836 0.64 MAPT (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109627483-A A kind of preparation method of melamine rigid closed-cell foam 四川金象赛瑞化工股份有限公司 2019-04-16 CN claimed
CN-109627483-A A kind of preparation method of melamine rigid closed-cell foam 四川金象赛瑞化工股份有限公司 2019-04-16 CN disclosed
CN-109627483-A A kind of preparation method of melamine rigid closed-cell foam 四川金象赛瑞化工股份有限公司 2019-04-16 CN disclosed