Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 7/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28286565 | 0.94 | MAOA (0.41) | MAOAMAOBMPOTRPV4DPP4 | |
| SCHEMBL16824548 | 0.94 | MAOA (0.41) | MAOAMAOBMPOTRPV4DPP4 | |
| SCHEMBL16824552 | 0.86 | MAOA (0.36) | MAOAMAOBMPOTRPV4DPP4 | |
| SCHEMBL14039187 | 0.77 | MAOA (0.42) | MAOAMAOBMPOTRPV4DPP4 | |
| SCHEMBL16313509 | 0.76 | AR (0.45) | MAOAMAOBMPOTRPV4DPP4 | |
| SCHEMBL27717690 | 0.76 | MAOA (0.39) | MAOAMAOBMPOTRPV4DPP4 | |
| SCHEMBL14010031 | 0.76 | MAOA (0.39) | MAOAMAOBMPOTRPV4DPP4 | |
| SCHEMBL16962135 | 0.76 | MAOA (0.41) | MAOAMAOBMPOTRPV4DPP4 | |
| SCHEMBL305457 | 0.76 | MAOA (0.41) | MAOAMAOBMPOTRPV4DPP4 | |
| SCHEMBL19437202 | 0.76 | MAOA (0.41) | MAOAMAOBMPOTRPV4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503551-A | The preparation method of one koji Ge Lieting | 安阳师范学院 | 2019-03-22 | — | — | CN | disclosed |