Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746026 | 0.82 | PRCP (0.58) | PRCPGID4TSHRNPSR1GAA | |
| Hydrochloric Acid SCHEMBL28061548 | 0.80 | GAA (0.59) | PRCPGID4TSHRNPSR1GAA | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL16291277 | 0.72 | PNMT (0.61) | HTR2AHTR2CHTR2B | |
| Indoline SCHEMBL27652752 | 0.72 | MAPK1 (0.45) | HTR2AHTR2CHTR2BSMN1; SMN2MAPT | |
| Tert-Butyl Formate SCHEMBL29029882 | 0.70 | PRCP (0.49) | PRCPHTR2AMAPT | |
| Tert-Butyl Formate SCHEMBL27951320 | 0.70 | TDP1 (0.52) | TSHRSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7136888 | 0.70 | PRCP (0.49) | PRCPGID4TSHRNPSR1GAA | |
| SCHEMBL4026574 | 0.70 | PRCP (0.49) | PRCPGID4TSHRNPSR1GAA | |
| Tert-Butyl Formate SCHEMBL27773262 | 0.69 | TDP1 (0.50) | HTR2C | |
| SCHEMBL30829405 | 0.68 | TSHR (0.60) | PRCPGID4TSHRNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109496213-A | Spiro-compound and its preparation and application | 阿比德治疗公司 | 2019-03-19 | — | — | CN | disclosed |