Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | AR | P10275 | 5/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404772 | 0.79 | HRH1 (0.43) | HTR1AHTR7HRH1SLC6A2SLC6A3 | |
| SCHEMBL31652114 | 0.79 | HRH1 (0.43) | HTR1AHTR7HRH1SLC6A2SLC6A3 | |
| SCHEMBL28425007 | 0.78 | MCHR1 (0.47) | HTR1AMCHR1HRH1SLC6A2SLC6A3 | |
| SCHEMBL29426955 | 0.77 | MCHR1 (0.39) | HTR1AMCHR1ARHRH1SLC6A2 | |
| SCHEMBL29165963 | 0.77 | HPGD (0.38) | HTR1AMCHR1ARHRH1SLC6A2 | |
| SCHEMBL20855449 | 0.77 | MCHR1 (0.39) | HTR1AMCHR1ARHRH1SLC6A2 | |
| SCHEMBL25385511 | 0.77 | SLC6A2 (0.47) | HTR1AMCHR1ARHRH1SLC6A2 | |
| SCHEMBL2824173 | 0.73 | KMT2A (0.33) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL25403030 | 0.73 | TLR8 (0.40) | MCHR1ARHRH1SLC6A2SLC6A3 | |
| SCHEMBL1926850 | 0.72 | KMT2A (0.44) | HTR1AMCHR1HRH1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178840-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall, S.A. (ES) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009021696-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2009-02-19 | — | — | WO | disclosed |